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Reference

Every ingredient, and what the research shows

One page per active in Moat, Keel and Spark. The form, the dose the studies actually used, what they found including when they found nothing, and who should be careful. No page here is a copy of another with the name swapped.

Ingredient

Vitamin C

Ascorbic acid at 180 mg a day. Regular supplementation does not stop you catching a cold; it modestly shortens the one you caught.

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Ingredient

Vitamin D3

Cholecalciferol, the strongest evidence in the bottle. Daily or weekly dosing lowers respiratory infection risk, most in people who start out low.

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Ingredient

Vitamin B6

Pyridoxal 5′-phosphate, the active form. Keel carries a high 26 mg because it sits inside a blend designed for people eating far less.

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Ingredient

Zinc

Zinc citrate in Moat at the everyday nutritional amount, zinc bisglycinate in Keel. The famous cold trials used lozenges at 80 to 207 mg, which is a different thing entirely.

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Ingredient

Elderberry Extract

Standardised Sambucus nigra fruit extract at 500 mg. The air-travel trial found no difference in who caught a cold, and a shorter, milder one in those who did.

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Ingredient

Vitamin B12

Methylcobalamin at 525 mcg. Both forms raise B12; neither has been shown clearly better for topping up a dietary gap in a healthy adult.

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Ingredient

Folate

L-5-MTHF-Ca at 400 mcg DFE, the active form. High folate can mask a B12 shortfall on a blood count, which is why the two travel together.

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Ingredient

Iron

Ferrous bisglycinate at 18 mg, a chelated form that is usually kinder to the stomach than oxide or sulfate at the same elemental amount.

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Ingredient

Magnesium

200 mg as oxide plus citrate. Magnesium draws water into the bowel, which is why the oxide form is the one that helps constipation.

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Ingredient

BioPerine®

Black pepper fruit extract at 5 mg. It raises the bioavailability of co-taken compounds, including curcumin and iron, and 5 mg is the studied amount.

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Ingredient

LactoSpore®

Bacillus coagulans at 166 mg, a spore-forming probiotic that survives stomach acid and reaches the gut alive.

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Ingredient

β-Nicotinamide Mononucleotide

500 mg at 99.9% purity. Blood NAD rises in human trials, and the dose-finding trial put 600 mg at the sweet spot.

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The other half

How we source all of this.

Every claim on this site cites the study it rests on, at the point the claim is made.

Our editorial policy
Made in the USAFDA-registered facilityGMP certifiedEvery dose printedNine good thingsThird-party tested