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Ingredient · 21 September 2026

Magnesium

200 mg as oxide plus citrate. Magnesium draws water into the bowel, which is why the oxide form is the one that helps constipation.

Written by R. Kessler · About Knurle · Editorial policy

The short answer

Magnesium is a mineral involved in muscle function, nerve signalling and hundreds of enzyme reactions. Magnesium oxide is poorly absorbed and draws water into the intestine, which is why it is the form used when the goal is bowel regularity rather than raising body magnesium.

The form, and why it matters

Oxide is the most concentrated and the least absorbed, and its osmotic effect is the point when constipation is the problem. Citrate is better absorbed and gentler. Glycinate is the best-tolerated and the least likely to loosen stools. Keel uses oxide plus citrate, which covers both jobs.

Typical dose

The adult reference intake is 310 to 420 mg a day depending on age and sex, from food and supplements together, with a supplemental tolerable upper intake of 350 mg for adults. Keel carries 200 mg.

What the research shows

Low magnesium is common in general diets, and whole grains, nuts and greens are the main sources, which are exactly the foods that shrink when appetite does. A 2025 study of combined magnesium and zinc found that correcting low levels of both improved fasting glucose and insulin sensitivity more than either alone, though these were corrections of deficiency rather than super-doses in replete people.

Who should be careful

High doses cause diarrhoea, which is the dose-limiting effect rather than a side effect to worry about. Magnesium supplements interact with several antibiotic classes and with levothyroxine, so separate the doses and ask a pharmacist.

Where it sits in our formulas

ProductForm on the labelAmount per serving% Daily Value
Keelas oxide + citrate200 mg48%

Sources

Figures checked against the sources above on 21 September 2026.

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